艾普定iProtin®表面聲波(SAW)核心技術平台
艾普定 iProtin® 是嘉碩生醫打造全新一代體外診斷解決方案，採用高頻反射式剪切水平表面聲波（SH-SAW）感測晶片，能即時偵測抗原抗體結合時在感測表面產生的質量與黏彈性變化，無需酵素或螢光標記，即可獲得高靈敏的定量或半定量檢測結果。得益於表面聲波技術的獨特物理性質，檢測過程不受血球干擾，可直接使用 5 μL 指尖全血樣本，並在 3 分鐘內完成高靈敏度分析。該平台技術已取得多國專利，具有高度延展性與模組化設計，能靈活應用於多種疾病標記物的檢測，包括心血管疾病、炎症指標與癌症相關蛋白等。
我們亦開放 艾普定 iProtin® 平台，供各大學術機構與企業合作開發生物晶片，促進表面聲波技術在多元 POCT 醫療應用中的落地與拓展。透過平台化設計與模組化架構，合作夥伴可專注於標的物的開發與驗證，加速創新檢測項目的實現與商品化。
支援客製化開發與 OEM/ODM 合作模式
除了創新的檢測平台，嘉碩生醫亦提供從晶圓製程到檢測生物晶片的一條龍製造服務，協助客戶快速完成產品化。 我們擁有專利級空腔封裝技術，可有效保護表面聲波感測晶片、提升訊號穩定性與可靠性；搭配10 nL 高精度生物材料塗佈技術，可有效降低生產成本及生物晶片微小化。
嘉碩生醫支 援客製化開發與 OEM/ODM 合作模式，可依需求設計晶片、封裝模組與生物塗佈方案，協助學研單位、新創公司或企業客戶從概念驗證、試產到量產順利落地。憑藉深厚的工程實力與製造經驗，我們致力成為次世代精準醫療領域最值得信賴的合作夥伴。
艾普定 iProtin® 檢測平台提供 API 介接功能，可整合個人健康指數、生活習慣與用藥紀錄，實現伴隨式診斷與個人化健康管理。
透過與穿戴裝置、健康雲平台或電子病歷系統的連結，使用者可即時依檢測結果調整運動強度、飲食內容或用藥劑量，
讓健康數據可視化，真正落實主動式、精準化的健康管理。
相關著作
2025
An Approach for Measuring Extracellular Vesicle Size Using the Attenuation-Velocity Change Ratio of SH-SAW Biosensors
Utilizing layer-parameter of shear horizontal surface acoustic wave biosensor for lipoprotein particle sizing
A Three-Channel Reflected SH-SAW Biosensor for Cardiovascular Risk Evaluation
2025 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)
DOI: 10.1109/IMBioC63524.2025.10989719
Published: 16 May 2025
2024
Tracking the Risk of Cardiovascular Disease after Almond and Oat Milk Intervene or Statin Medication with a Powerful Reflex SH-SAW POCT Platform
Sensor 2024, 24(20), 6517, Link to article
Published: 10 October 2024
New Advances in Rapid Pretreatment for Small Dense LDL Cholesterol Measurement Using Shear Horizontal Surface Acoustic Wave (SH-SAW) Technology
Research article , Int. J. Mol. Sci. 2024, 25(2), 1044 Link to article
Published: 15 January 2024
2023
Sensitivity Measurement For a 250 MHz Quartz Shearhorizontal Surface Acoustic Wave Biosensor Nnder Liquid Viscous Loading
Research article , AIP advances 13, 125305 (2023) Link to article
Published: 06 December 2023
Application of Shear Horizontal Surface Acoustic Wave (SH-SAW) Immunosensor in Point-of-Care Diagnosis
Biosensors 2023, 13(6), 605; Link to article
Published: 1 June 2023
2022
Measurements of Anti-SARS-CoV-2 Antibody Levels after Vaccination Using a SH-SAW Biosensor
Biosensors 2022, 12(8), 599; Link to article
Published: 4 August 2022
2021
A Novel Rapid Test to Detect Anti-SARS-CoV-2 N Protein IgG Based on Shear Horizontal Surface Acoustic Wave (SH-SAW)
DOI: https://doi.org/10.3390/diagnostics11101838
Published: 5 October 2021
Evaluation of Shear Horizontal Surface Acoustic Wave Biosensors Using “Layer Parameter” Obtained from Sensor Responses during Immunoreaction
DOI: https://doi.org/10.3390/s21144924
Published: 20 July 2021
2019
Precipitate-enhanced SAW immunosensor for sensitive monitoring of mite allergens
DOI:10.1016/J.SNB.2019.05.056
Published 2019
Repeated immunosensing by a dithiobis(succinimidyl propionate)-modified SAW device
Published 2019
ISSN: 0039-9140
EISSN: 1873-3573
DOI: 10.1016/j.talanta.2019.05.080
PMID: 31202338
A Prototype Antibody-based Biosensor for Measurement of Salivary MMP-8 in Periodontitis using Surface Acoustic Wave Technology
Published in Scientific Reports volume 9, Article number: 11034 (2019)
Published 30 July 2019
2018
Rapid C-Reactive Protein Measurement by SH-SAW Based Immunoassay
Published in Seventh International Symposium on Acoustic Wave Devices for Future Mobile Communication Systems
Published 6 March 2018
Ultra-rapid, sensitive and specific digital diagnosis of HIV with a dual-channel SAW biosensor in a pilot clinical study
Published 17 August 2018
2017
Temperature dependence of immunoreactions using shear horizontal surface acoustic wave immunosensors
Published 12 June 2017
A gold nanoparticle-assisted sensitive SAW (surface acoustic wave) immunosensor with a regeneratable surface for monitoring of dust mite allergens
Published in 2017
JST Material Number： T0967A
ISSN： 0925-4005
Rapid and repetitive immunoassay with a surface acoustic wavedevice for monitoring of dust mite allergens
Published in 2017
journal ISSN :0925-4005
DOI10.1016/j.snb.2017.01.183
Rayleigh SAW-Assisted SH-SAW Immunosensor on X-Cut 148-Y LiTaO3
Published in: 2016 IEEE International Ultrasonics Symposium (IUS)
Date of Conference: 18-21 Sept. 2016
Electronic ISSN: 1948-5727
DOI: 10.1109/ULTSYM.2016.7728562
Towards an ultra-rapid martphone-connected test for infectious diseases
Published: 20 Sep 2017
DOI: 10.1038/s41598-017-11887-6
Semicontinuous Measurement of Mite Allergen (Der f 2) Using a Surface Acoustic Wave Immunosensor under Moderate pH for Long Sensor Lifetime
Published: December 22, 2017
2016
SH-SAW biosensor on quartz
Published in: 2016 IEEE International Frequency Control Symposium (IFCS)
Date of Conference: 9-12 May 2016
DOI: 10.1109/FCS.2016.7546725
Rayleigh SAW-Assisted SH-SAW Immunosensor on X-Cut 148-Y LiTaO 3
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control ( Volume: 64, Issue: 9, Sept. 2017)
Page(s): 1375 - 1381
Date of Publication: 31 July 2017
PubMed ID: 28783630
DOI: 10.1109/TUFFC.2017.2734282
2015
Rapid Diagnositic Tests Using SH-SAW Immunosensor
Published in: Sixth International Symposium on Acoustic Wave Devices for Future Mobile Communication Systems
Published 24 November 2015
Effect of viscoelastic film for shear horizontal surface acoustic wave on quartz
Published 20 May 2015
Repetitive Immunoassay with a Surface Acoustic Wave Device and a Highly Stable Protein Monolayer for On-Site Monitoring of Airborne Dust Mite Allergens
Published in: analytical chemistry
Published online29 September 2015
Numerical Analysis of Viscosity Effect on Shear Horizontal Surface Acoustic Wave for Biosensor Application
Published in : IEEJ Transactions on Sensor and Micromachines
Published: January 01, 2016
2014
Liquid-Phase Membrane-Type Shear Horizontal Surface Acoustic Wave Devices
Published in : Sensors and Materials, Vol. 26, No. 8 (2014) 599–606
Published 2014
Shear-horizontal surface acoustic wave biosensors for POCT
Published in: 2014 IEEE International Frequency Control Symposium (FCS)
Date of Conference: 19-22 May 2014
Electronic ISBN:978-1-4799-4915-1
DOI: 10.1109/FCS.2014.6859843
Simulation for viscoelastic effects of SH-SAW biosensor
Published in: 2014 IEEE International Ultrasonics Symposium
Date of Conference: 3-6 Sept. 2014
Print ISSN: 1051-0117
DOI: 10.1109/ULTSYM.2014.0511
2013
Analysis of Mass Loading Effect on Guided Shear Horizontal Surface Acoustic Wave on Liquid/Au/Quartz Structure for Biosensor Application
Published in :Japanese Journal of Applied Physics
Published 20 June 2013
2012
High-Performance Surface Acoustic Wave Immunosensing System on a PEG/Aptamer Hybridized Surface
Published in : Langmuir
Published online19 March 2013
Measurement Characteristics of Flow-Type Shear-Horizontal Surface Acoustic Wave Sensor for Direct Methanol Fuel Cells
Published 20 July 2012
Numerical analysis of liquid-phase SH-SAW biosensor on quartz
Published in: 2012 IEEE International Ultrasonics Symposium
Date of Conference: 7-10 Oct. 2012
DOI: 10.1109/ULTSYM.2012.0527
SH-SAW Biosensor for POCT Applications
Published in :2012 International Symposium on Acoustic Wave Devices for Future Mobile Communication Systems
Published 6 December 2012
2011
3F-3 Liquid Sensor Using SAW and SH-SAW on Quartz
Published in: 2006 IEEE Ultrasonics Symposium
Date of Conference: 2-6 Oct. 2006
Print ISSN: 1051-0117
DOI: 10.1109/ULTSYM.2006.143
STW gas sensors using plasma-polymerized allylamine
Published 2007
JST Material Number： O6387A
ISSN： 0040-6090
Liquid-Phase Sensor Using SH-SAW on Quartz
Published in :Proceedings of the IEEE Ultrasonics Symposium 1:552 - 555
Published November 2006
DOI :10.1109/ULTSYM.2006.143
STW gas sensors using plasma-polymerized allylamine
Published in: Thin Solid Films Published 2007
ISSN:10510117
Source publication type: Journal
DOI: 10.1109/ULTSYM.2002.1193343
Dip-type Liquid-Phase Sensor Using SH-SAW
Published in: IEEE Xplore2007 IEEE Ultrasonics Symposium Proceedings
Date of Conference: 28-31 Oct. 2007
Print ISSN: 1051-0117
DOI: 10.1109/ULTSYM.2007.526
Improvement of Liquid-Phase SH-SAW sensor device on 36º Y-X LiTaO3 substrate
Published in: 2008 IEEE Ultrasonics Symposium
Date of Conference: 2-5 Nov. 2008
Print ISSN: 1051-0117
DOI: 10.1109/ULTSYM.2008.0024
liquid-Phase SH-SAW immunoassay sensor
Published in:Fourth International Symposium on Acoustic Wave Devices for Future Mobile Communication Systems
Published 3 March 2010
Liquid-Phase Shear Horizontal Surface Acoustic Wave Immunosensor
Published 20 July 2010
Point-of-care SH-SAW biosensor
Published in: 2010 IEEE International Ultrasonics Symposium
Date of Conference: 11-14 Oct. 2010
DOI: 10.1109/ULTSYM.2010.5935551
SH-SAW liquid sensor for methanol concentration sensing
Published in: 2010 IEEE International Ultrasonics Symposium
Date of Conference: 11-14 Oct. 2010
DOI: 10.1109/ULTSYM.2010.5935550